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PGx testing for mental health
Go from trial and error to test and treat
Pharmacogenomics, also known as PGx, is the study of how a person's genes affect how he or she responds to medications. The goal of PGx is to help doctors personalize a patient’s treatment - selecting the drugs and doses best suited for each individual patient. IDgenetix is an advanced precision medicine solution that sets a new standard for comprehensive tailored PGX testing. Our unique bioinformatics platform integrates drug-gene, drug-drug metabolic interactions and lifestyle factors into a clinically actionable report.
The mental health crisis in the U.S.
90% of adults
say the United States is experiencing a mental health crisis (KFF/CNN Survey, 2022)
1 in 5 adults
experienced mental illness in 2021 (SAMHSA National Survey, 2021)
Half of patients
with mental illness will go untreated or undertreated (Mental Health America, 2023)
Trial and error consequences
No mental health treatment is right for everyone. A complex interplay of factors impacts how fast a patient will metabolize a medication, the side effects they experience, and whether the medication will help the patient reach remission.
Without tools to help predict a patient’s response to medications, clinicians have had to resort to trial and error. For many, the path to the right treatment can be long, hard, and discouraging - patients may try multiple drugs and wait many months before they find one that works and has tolerable side effects.
4–6 weeks
trial period before medication response can be assessed (NICE, 2009)
52%
of patients take more than one medication (Zhong, et al. 2013)
1 in 5 patients
have problematic drug-drug interactions (Kanaan, et al. 2013)
The landmark STAR*D depression study showed that 53% of patients inadequately responded to their first-line treatment, and that finding an effective treatment could take years. (Trivedi, 2006)
With each successive treatment, patients were:
-
1
More likely to discontinue treatment due to side effects
-
2
Less likely to achieve remission
IDgenetix – 3 in 1 PGx Testing
IDgenetix helps to inform more personalized mental health treatment by accounting for more factors that can influence a patient’s response to medication than any other PGx test, including drug-drug interactions.
Drug-gene interactions
Drug-drug interactions
Lifestyle factors & environment
Rethink medication selection. Increase remission rates.
Trial and error no longer needs to be the standard of care for mental health treatment. IDgenetix is a comprehensive pharmacogenomic test proven to help improve medication response and remission rates.
In a randomized controlled trial, patients whose clinicians received their IDgenetix results had a better chance of responding to medication and achieving remission.
Patients who received IDgenetix-guided treatment:
Were 2x more likely
to respond to treatment at 12 weeks (Bradley, et al. 2018)
Had 2.5x higher rates
of remission at 12 weeks (Bradley, et al. 2018)
Your prescription for more personalized mental health treatment
IDgenetix testing uses pharmacogenomics (PGx) along with other relevant factors to help predict a patient's response to medication before they take it, and develop personalized medication profiles for patients.
Pharmacogenomics, also known as PGx, is the study of how a person’s genes affect how they respond to medications. The goal of PGx is to help doctors personalize a patient’s treatment - selecting the drugs and doses best suited for each individual patient.
PGx testing helps to determine a person’s metabolic phenotype - how their genes will impact their metabolism of drugs. Some people have genes that cause them to metabolize medicine very rapidly. Individuals with gene mutations associated with rapid metabolism may require higher doses of a medicine for it to have the same effect as someone with a lower metabolism. They may also experience fewer side effects.
There are numerous factors that can influence how a patient will respond to a medication. In addition to how a patient is likely to metabolize a drug, IDgenetix helps to identify drug-drug interactions that may occur based on other medications a patient is taking, as well as lifestyle and environmental factors that may impact how a patient responds to a medication and the side effects a patient may experience.
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